Every day we are on the move. Every day we have to endure some discomfort, which kills in us all the strength and desire. On the treatment of these problems vocation medication. Substances capable to heal wounds, soothe the nerves, lead us to a normal state. Such as drug Spironolactone called to solve the most complicated problems. Spironolactone is a potassium-sparing diuretic and a competitive antagonist of aldosterone. In simple words, this means that what is required to help you with your problems.
Generic Aldactone contain substance that is called Spironolactone and you can use Spironolactone, it stops the aldosterone sodium and water in the body, suppresses potassium excurrent effect, reduces the synthesis of permeases in the aldosterone. It is said that Aldactone making contact with aldosterone receptors, increases the excretion of sodium, chloride and water in the urine, thereby reducing the excretion of potassium ions and moeviny. It is noteworthy property of reducing the acidity of urine into the body. Unstable effect of hypotension is caused by increased urine output. The effect is a registered maximum 7 hours after drug administration by mouth, and dlyalsya least 24 hours. The effect is manifested as a diuretic for 2-5 days of treatment.
Distribution: binds to plasma proteins is 98%.
Metabolism during biotransformation in the liver metabolites formed active sulfur.
Excretion: derived primarily in the urine (50% as metabolites, 10: – the constant appearance)
Indications for admission Spironolactone:
edema syndrome in patients with chronic heart failure
states in which secondary aldosteronism detected
It is also worth noting measuring mode:
Daily norm for normal adults is 50-100 mg Spironolactone singly, but may be increased to 200 mg. Appropriate responses to drug therapy, it is necessary to take at least 2 weeks.
While improving, when the dose of Spironolactone is decreased to 25 mg / day.
And anyway, Spironolactone 25mg is a normal dose for an easy stage disease.
Not to be missed and the possibility of side-effects:
Of phenomena in the digestive system it is worth noting nausea, vomiting, diarrhea. Touch upon the central nervous system, ataxia, confusion, dizziness. On the part of the blood system, agranulocytosis, thrombocytopenia. From a metabolism, hyperuricemia, increased concentrations of urea. Part of the endocrine system, deepening of the voice, and various side effects in men (gynecomastia, erectile dysfunction and decreased potency), as well as in women (menstrual disorders, dysmenorrhea, amenorrhea). Allergic reaction: hives. Dermatological reactions: alopecia, hypertrichosis. Urine may also suffer, acute renal failure.
Our drug kotorvy you can use Spironolactone, as there are contraindications, it is worth noting the main ones:
– Addison’s disease;
– Severe renal insufficiency (creatinine clearance less than 10 ml / min);
– Hypersensitivity to any component of the drug.
I do not recommend messing at all with any medicines, and especially with such as Spironolactone, which may cause a negative reaction in the synthesis of a body. These drugs are never used for medicine purposes. Be sure to consult a physician, because our store provides Spironolactone, allowing you much faster and easier to make a purchase.
Everything is done for you! And so we are pleased to announce the online service allows you to get Spironolactone. You can use Spironolactone easily, simply and with all the convenience. Without further ado and effort.
Just want to mention the price Spironolactone in our store, it amazes even doctors, unnatural cheapness is due to a simple sentence: we get Spironolactone a product from the manufacturer. Spironolactone, does not mean its useless, it just means that the desire to help you overpowering desire for profit. At reasonable prices in our store you can find a drug Spironolactone 25mg, as well as Spironolactone 100mg.